Squalane
Ingredient Type: Emollient
Highlights
- Helps soften and smooth the skin
- Helps reduce moisture loss from the skin
- Supports the skin barrier
- Lightweight and fast-absorbing
The Science
Squalane is derived from squalene, a lipid naturally found in human sebum that helps keep the skin soft and supple. Squalane is the hydrogenated form of squalene, making it more stable for use in skincare products while retaining many of the same skin-conditioning properties. Because it closely resembles components naturally present in the skin, squalane is readily accepted by the skin and absorbs easily without leaving a heavy or greasy feel.
Squalane functions as an emollient, forming a lightweight protective layer on the skin’s surface that helps reduce transepidermal water loss (TEWL). By helping prevent moisture from escaping, squalane supports the skin barrier and helps maintain hydration, leaving the skin feeling softer, smoother, and more supple.
Did You Know?
Squalane was once commonly sourced from shark liver oil. Today, most cosmetic squalane is derived from plant sources such as sugarcane and olives. Dermaphilic uses sugarcane-derived squalane in its formulations.
Common Questions
What skin benefits does squalane offer?
Squalane helps soften and smooth the skin while supporting the skin barrier and maintaining hydration. By helping reduce moisture loss, it can leave the skin feeling softer, smoother, and more supple.
Does squalane clog pores, and what skin types is it good for?
Squalane is generally suitable for a wide range of skin types, including dry, normal, combination, oily, and sensitive skin. It is lightweight, absorbs easily, and is considered non-comedogenic.
Where You'll Find It
You'll find squalane in Dermaphilic's Black Seed + Squalane Facial Oil.
Last Updated: June 15, 2026
References
Huang, Z.-R., Lin, Y.-K., & Fang, J.-Y. (2009). Biological and pharmacological activities of squalene and related compounds: Potential uses in cosmetic dermatology. Molecules, 14(1), 540–554.
Kim, S.-K., & Karadeniz, F. (2012). Biological importance and applications of squalene and squalane. Advances in Food and Nutrition Research, 65, 223–233.
Purnamawati, S., Indrastuti, N., Danarti, R., & Saefudin, T. (2017). The role of moisturizers in addressing various kinds of dermatitis: A review. Clinical Medicine & Research, 15(3–4), 75–87.